Replacing daily cART with AAV-expressed eCD4-Ig
نویسندگان
چکیده
منابع مشابه
eCD4-Ig promotes ADCC activity of sera from HIV-1-infected patients
Antibody-dependent cell-mediated cytotoxity (ADCC) can eliminate HIV-1 infected cells, and may help reduce the reservoir of latent virus in infected patients. Sera of HIV-1 positive individuals include a number of antibodies that recognize epitopes usually occluded on HIV-1 envelope glycoprotein (Env) trimers. We have recently described eCD4-Ig, a potent and exceptionally broad inhibitor of HIV...
متن کاملReplacing Make with Haskell
Most complex software projects are compiled using a build tool (e.g. make), which runs commands in an order satisfying userdefined dependencies. Unfortunately, most build tools require all dependencies to be specified before the build starts. This restriction makes many dependency patterns difficult to express, especially those involving files generated at build time. We show how to eliminate t...
متن کاملImproved Immunological Tolerance Following Combination Therapy with CTLA-4/Ig and AAV-Mediated PD-L1/2 Muscle Gene Transfer
Initially thought as being non-immunogenic, recombinant AAVs have emerged as efficient vector candidates for treating monogenic diseases. It is now clear however that they induce potent immune responses against transgene products which can lead to destruction of transduced cells. Therefore, developing strategies to circumvent these immune responses and facilitate long-term expression of transge...
متن کاملReplacing dairy milk with soy
Many people drink dairy milk (from a cow) as a healthy source of calcium and protein. In every eight-ounce cup of dairy milk, there are eight grams of protein and twelve grams of carbohydrates. It?s also rich in other nutrients as well: one cup provides adults with about 30 percent of their daily calcium needs and about 50 percent of their vitamin B12 and riboflavin requirements. Despite these ...
متن کاملReplacing dairy milk with soy
Many people drink dairy milk (from a cow) as a healthy source of calcium and protein. In every eight-ounce cup of dairy milk, there are eight grams of protein and twelve grams of carbohydrates. It?s also rich in other nutrients as well: one cup provides adults with about 30 percent of their daily calcium needs and about 50 percent of their vitamin B12 and riboflavin requirements. Despite these ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Virus Eradication
سال: 2019
ISSN: 2055-6640
DOI: 10.1016/s2055-6640(20)30200-4